Non-invasive mechanical ventilation in critically ill trauma patients: A systematic review [Turk J Anaesthesiol Reanim]
Turk J Anaesthesiol Reanim. 2018; 46(2): 88-95 | DOI: 10.5152/TJAR.2018.46762  

Non-invasive mechanical ventilation in critically ill trauma patients: A systematic review

Annia Schreiber1, Fatma Yıldırım2, Giovanni Ferrari3, Andrea Antonelli4, Pablo Bayoumy Delis5, Murat Gündüz6, Karez Marcin7, Peter Papadakos8, Roberto Cosentini9, Yalım Dikmen10, Antonio M Esquinas5
1Fondazione Salvatore Maugeri, IRCCS, Respiratory Intensive Care Unit and Pulmonary Rehabilitation Unit, Pavia, Italy
2Ankara Dışkapı Yıldırım Beyazıt Research and Education Hospital, Intensive Care Unit, Ankara, Turkey
3Ospedale Mauriziano, Department of Respiratory Medicine, Turin Italy
4Allergologia e Fisiopatologia Respiratoria, ASO S. Croce e Carle Cuneo, Cuneo, Italy.
5Hospital Morales Meseguer, Intensive Care Unit, Murcia, Spain.
6Cukurova University, Faculty of Medicine, Department of Anesthesiology and Reanimation, Intensive Care Unit, Adana, Turkey
7University of Rochester, Department of Anesthesiology, Critical Care Medicine, Rochester, New York
8University of Rochester, Department of Anesthesiology,Surgery and Neurosurgery, Critical Care Medicine, Rochester, New York
9Emergency Medicine Department, Gruppo NIV, Fondazione IRCCS Ca
10Istanbul University, Cerrahpaşa Medical School, Department of Anesthesiology and Reanimation, Intensive Care Unit, Istanbul, Turkey

The literature on non-invasive mechanical ventilation (NIMV) in patients with polytrauma-related acute respiratory failure (ARF) is very limited. Despite increasing worldwide application, there is still a scarce evidence of significant benefit of NIMV in this specific setting and no clear recommendations are provided.
We performed a systematic review and a search of clinical databases including MEDLINE and EMBASE was carried out from the beginning of 1990 until the day.
Even though of unclear benefit in reducing intubation rate, morbidity and mortality, NIMV may be useful and does not appear associated with harm when applied in moderate ARF in properly selected patients at an earlier stage of injury by experienced teams and in appropriate settings under strict monitoring. In the presence of these criteria, NIMV is worth attempting but only if endotracheal intubation is promptly available, as non-responders to NIMV are burdened by an increased mortality when intubation is delayed.

Keywords: Non-invasive mechanical ventilation, continuous positive airway pressure, acute lung injury, acute respiratory distress syndrome, acute respiratory failure, transfusion-associated circulatory overload.


Annia Schreiber, Fatma Yıldırım, Giovanni Ferrari, Andrea Antonelli, Pablo Bayoumy Delis, Murat Gündüz, Karez Marcin, Peter Papadakos, Roberto Cosentini, Yalım Dikmen, Antonio M Esquinas. Non-invasive mechanical ventilation in critically ill trauma patients: A systematic review. Turk J Anaesthesiol Reanim. 2018; 46(2): 88-95

Corresponding Author: Annia Schreiber, Italy


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