Brain Death and Organ Donation in Paediatric Intensive Care Unit [Turk J Anaesthesiol Reanim]
Turk J Anaesthesiol Reanim. 2019; 47(1): 55-61 | DOI: 10.5152/TJAR.2019.43726  

Brain Death and Organ Donation in Paediatric Intensive Care Unit

Sengül Özmert1, Feyza Sever1, Ganime Ayar2, Mutlu Uysal Yazıcı3, Dilek Kahraman Öztaş4
1Department of Anaesthesiolgy and Reanimation, University of Health Sciences Ankara Child Health and Diseases Haematology Oncology Training and Research Hospital, Ankara, Turkey
2Department of Paediatric Intensive Care Unit, University of Health Sciences Ankara Child Health and Diseases Haematology Oncology Training and Research Hospital, Ankara, Turkey
3Department of Paediatric Intensive Care Unit, Hacettepe University İhsan Dogramacı Children’s Hospital, Ankara, Turkey
4Department of Public Health, Yıldırım Beyazıt University School of Medicine, Ankara Atatürk Training and Research Hospital, Ankara, Turkey

Objective: The purpose of the present study was to retrospectively analyse the brain death (BD) cases that were specified within the last 8 years in the paediatric intensive care unit of our hospital.
Methods: Archive files and computer records of 23 paediatric cases were analysed. Data on age, gender, conditions that caused BD, paediatric risk of mortality (PRISM III) scores, time between suspicion of BD and issuing of BD report, confirmatory tests used, complications that occurred following the diagnosis of BD and time to cardiac arrest development after diagnosis of BD were recorded.
Results: The average age of the patients was 6.8±5.5 years. The most frequent cause of BD was intracranial haemorrhage (30.4%). The mean time to diagnosis after BD suspicion was 5.9±6.2 days. Electroencephalography was performed in 61% of the patients in addition to the apnoea test. Radiological imaging methods were used in 39% of the patients (n=9). Of the cases, 34.7% developed hypothermia, and 4.3% developed diabetes insipidus (DI). Among them, 43.4% had both DI and hypothermia. The mean PRISM score was calculated as 22±9.2. The donation rate of the families was 17%. The mean time to cardiac arrest development after diagnosis of BD was 6.9±7.4 days in non-donor cases where medical support had been reduced.
Conclusion: Any patient with a neurologically poor prognosis in the intensive care unit should be considered to develop BD and diagnosed with BD without delay. The donation rate will increase if family interviews are done by an experienced and educated coordinator.

Keywords: Brain death, child, organ donation


Sengül Özmert, Feyza Sever, Ganime Ayar, Mutlu Uysal Yazıcı, Dilek Kahraman Öztaş. Brain Death and Organ Donation in Paediatric Intensive Care Unit. Turk J Anaesthesiol Reanim. 2019; 47(1): 55-61

Corresponding Author: Sengül Özmert, Türkiye


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