Chlorhexidine allergy: mild allergic reactions can precede anaphylaxis in the healthcare setting – a case report [Turk J Anaesthesiol Reanim]
Turk J Anaesthesiol Reanim. Ahead of Print: TARD-22058

Chlorhexidine allergy: mild allergic reactions can precede anaphylaxis in the healthcare setting – a case report

Morten Schjørring Opstrup1, Lene Heise Garvey2
1Department of Dermatology, Zealand University Hospital, Roskilde, Denmark and Danish Anaesthesia Allergy Centre, Allergy Clinic, Department of Dermatology and Allergy, Copenhagen University Hospital Gentofte, Denmark
2Danish Anaesthesia Allergy Centre, Allergy Clinic, Department of Dermatology and Allergy, Copenhagen University Hospital Gentofte, Denmark and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark

Chlorhexidine can cause severe immediate-type allergic reactions such as urticaria, anaphylactic shock or even cardiac arrest. We report a patient who developed perioperative anaphylactic shock caused by chlorhexidine one year after a postoperative urticarial reaction, which was not thought significant at the time. This case highlights the importance of identifying mild allergy symptoms after exposure to chlorhexidine at the pre-anaesthetic assessment, to prevent further and more severe allergic reactions.

Keywords: allergy, anaphylaxis, chlorhexidine, perioperative, drug allergy




Corresponding Author: Morten Schjørring Opstrup, Denmark


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